What Is Fetal Fibronectin (fFN)?

Fetal fibronectin (fFN) is a protein produced during pregnancy, which functions as a ‘glue’ attaching the fetal sac to the uterine lining.1

The presence of fFN during weeks 22-36 of a high-risk pregnancy, along with symptoms of labour suggests that the ‘glue’ is disintegrating ahead of schedule and raises the possibility of preterm delivery.2



  1. MedicineNet.com. Medical Definition of Fetal fibronectin. September 2016. Available at: https://www.medicinenet.com/script/main/art.asp?articlekey=23860
  2. Rapid fFN 10Q Cassette Package Insert, AW-09189-001-002-02, Marlborough MA, Hologic Inc. 2015

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