What does the research say?

The fFN test is the only named biomarker test recommended in the NICE guidelines for the risk assessment of preterm labour and birth1 and comes with a strong body of evidence supporting its use in the clinical setting.

A clinically proven, powerful indicator for planning and peace of mind

fFN testing has been shown to precisely measure the concentration of the fFN protein to help quantify the risk of preterm labour and birth in both patients who have symptoms of preterm labour and those at high-risk.2

In this section you will find links to clinical papers, including four reviewed clinical papers that discuss the development and provision of the fFN test.

Professor Anna David, Consultant in Obstetrics and Maternal Fetal Medicine, UCLH
Dr Manju Chandiramani, Consultant Obstetrician, Guys and St Thomas' NHS Foundation Trust
Paper 1
Abbott et al.
Paper 2
Hezelgrave et al.
Paper 3
Kuhrt et al.
Paper 4
Abbott et al.
Paper 5
Foster C. et al.
Paper 6
Hezelgrave et al.

To find out more about fFN testing, please submit the enquiry form.


  1. National Institute for Health and Care Excellence (NICE). Preterm labour and birth guidance. Published November 2015. Available at: https://www.nice.org.uk/guidance/ng25/chapter/recommendations#diagnosing-preterm-labour-for-women-with-intact-membranes
  2. Rapid fFN for the TliIQ System [package insert]. AW-04196-002, Rev. 003. Marlborough, MA: Hologic, Inc.; 2015.

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Caution: The QuikCheck fFNTest is not sold or offered for sale in the United States or Canada.



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